An International Journal of Advances in Pharmaceutical Sciences Volume 6|Issue 2|March-April 2015|Pages XXXX-XXXX EVALUATION OF ANTIHYPERGLYCEMIC, ANTIHYPERLIPIDEMIC AND ANTIOXIDANT ACTIVITY OF SOME NOVEL SYNTHETIC PIPERONAL DERIVATIVES

Piperonal, also known as heliotropin, is an organic compound that is commonly found in fragrances and flavors. The molecule is structurally related to benzaldehyde and vanillin. Currently available hypoglycemic agents used in allopathic medication have many side effects such as skin rashes, dilutional hyponatremia, transient leucopenia, thrombocytopenia, myocarditis and sever hypoglycemia and increased chances of cardiovascular death. The condition becomes more alarming when one considers the complications associated with the disease, the substantial cost burden that the disease imposes to society and in particular to those individuals with diabetes and their families and the various side effects that are associated with the various drugs used for management of the disease. Management of diabetes with agents devoid of any side effect is still challenge to the medical profession. Therefore, the search for more effective and safer hypoglycemic agents have continued to be an important area for research.